diff --git a/src/renderer/src/config/models.ts b/src/renderer/src/config/models.ts
index 015e8ad0..230701bd 100644
--- a/src/renderer/src/config/models.ts
+++ b/src/renderer/src/config/models.ts
@@ -2220,6 +2220,13 @@ export function isSupportedReasoningEffortModel(model?: Model): boolean {
   return false
 }
 
+export function isGrokModel(model?: Model): boolean {
+  if (!model) {
+    return false
+  }
+  return model.id.includes('grok')
+}
+
 export function isGrokReasoningModel(model?: Model): boolean {
   if (!model) {
     return false
diff --git a/src/renderer/src/providers/AiProvider/OpenAIProvider.ts b/src/renderer/src/providers/AiProvider/OpenAIProvider.ts
index b78bf2c1..518bedc0 100644
--- a/src/renderer/src/providers/AiProvider/OpenAIProvider.ts
+++ b/src/renderer/src/providers/AiProvider/OpenAIProvider.ts
@@ -1,6 +1,7 @@
 import { DEFAULT_MAX_TOKENS } from '@renderer/config/constant'
 import {
   getOpenAIWebSearchParams,
+  isGrokModel,
   isGrokReasoningModel,
   isHunyuanSearchModel,
   isOpenAIoSeries,
@@ -382,9 +383,13 @@ export default class OpenAIProvider extends BaseProvider {
     const { signal } = abortController
     await this.checkIsCopilot()
 
-    const reqMessages: ChatCompletionMessageParam[] = [systemMessage, ...userMessages].filter(
-      Boolean
-    ) as ChatCompletionMessageParam[]
+    // Grok 模型要求每条消息都不能为空，所以当是 Grok 模型且 systemMessage 内容为空时不发送 systemMessage
+    let reqMessages: ChatCompletionMessageParam[]
+    if (isGrokModel(model) && !systemMessage.content) {
+      reqMessages = [...userMessages]
+    } else {
+      reqMessages = [systemMessage, ...userMessages].filter(Boolean) as ChatCompletionMessageParam[]
+    }
 
     const toolResponses: MCPToolResponse[] = []
     let firstChunk = true